The "Wild 'N Out" host's goal is "to help find a cure for pediatric cancer, further research and help console more families during difficult times."
The musician's son, Matt Tuggle, confirmed the sad news.
"She doesn’t quite understand that he’s not coming back,” the late singer's wife, Kelsey Parker, said in a new interview. "So I have to be really blunt."
The country music star was diagnosed in the fall and has been undergoing treatment for the past six months. "I need time to breathe, recover and relax."
The toddler recently began chemotherapy and has already had surgery for the "placement of a port line, a bone marrow biopsy and a lumbar puncture."
"The Big Lebowski" star revealed he nearly died while battling both coronavirus and non-Hodgkin lymphoma during a five-month hospital stint in 2021.
The singer called Sheeran a "special man," and said his kind gesture "meant the world" to him and his wife, Kelsey Parker.
The actress, who was raped during a home invasion in 1985, thinks her weakened immune system from not processing the trauma was one reason she got cancer in 2000.
Dow, who played the Beav's older brother, Wally Cleaver, on the classic sitcom, did not reveal what type of cancer he has.
"I'm a puddle every time I think about what Amber is going through, but she is being so courageous and is handling it extremely well," the "GMA" anchor shared.